This technology presents three porcine macrophage-derived single-cell clones that express the porcine reproductive and respiratory syndrome virus (PRRSV) entry receptor, CD163. Each clone permits viral entry but differs in its ability to support post-entr...
This technology uncovers more about the key virulence factors of Japanese encephalitis virus (JEV), a neuroinvasive and neurovirulent orthoflavivirus, laying the groundwork for molecular markers for improving the JEV vaccine.
Hepatitis B virus (HBV) is a major global health challenge that infects the liver and can lead to both acute and chronic disease. Approximately 254 million people worldwide live with chronic HBV, with an estimated 1.2 million new infections and 1.1 millio...
This study identifies the genetic changes required for a weakened Junin vaccine virus to regain virulence. That insight guides the engineering of safer, more genetically stable live vaccines with a lower risk of reverting to a harmful form.
This technology uses recombinant hagfish proteins and spider silk proteins to create a viable process for neural regeneration.
Reactive oxygen species (ROS)-induced diseases pose a significant challenge in modern medicine, necessitating innovative therapeutic and preventive strategies. By leveraging hydrophobic nanoparticles (NP), antioxidants can be effectively delivered to lipo...
This innovation introduces a new class of tertiary Mg/MgCl2/AlCl3 (MMAC) inorganic Mg2+ electrolytes in ethereal solvents that enable highly reversible Mg plating/stripping with dramatically reduced overpotentials and near‑unity Coulombic efficiency after...
USU researchers have developed a customizable, novel eye contact lens inspired by the reflective, sub-micron spaced lamellae in the eyes of elephantnose fish. This innovation improves color perception in people with red-green color deficit while maintaini...
Uridine diphosphate glucuronyltansferase (UGT) in Streptomyces chromofuscus can be used to prepare different polyphenol glucuronides to effectively increase water solubility and bioavailability of drugs. This enzyme has broad substrate specificity, and th...
This technology enables crop hybrids to clone themselves through their own seed. It has the potential to disrupt the trillion dollar commercial seed industry by cutting seed production costs by 80% for crops currently produced as hybrids and enabling the
USU researchers have designed a one-step, inexpensive synthesis of amphiphilic alkyl kanamycins (AKs) that uses all-natural components. The result is a new antifungal compound, KI07, which has in vitro activity against fungal pathogens.
Transgenic Mouse Model with Tunable NAD+ Deficiency: NAD+ deficiency is a common factor of aging and a number of metabolic and neurodegenerative diseases. USU researchers have developed methods to create a mouse model with tunable and reversible NAD+ defi...