Controlled Biologics & Chemicals
The two main bodies of export control regulations, ITAR and EAR, restrict the international transfer of certain biologics (bacteria, fungi, toxins, or viruses) and chemicals. A list of restricted biologics and chemicals can be found below. These restrictions are imposed for national security and safety reasons. USU personnel must ensure their use or transfer of restricted biologics or chemicals complies with applicable regulatory requirements.
Shipping Restricted Biologics or Chemicals Internationally
If you wish ship biologics or chemicals from the list below internationally, please complete the USU International Shipment Review Form, which allows the Research Integrity & Compliance (RIC) office to review the transaction, and determine if a license from the U.S. State or Commerce Departments is required prior to shipping to the intended recipient.
Obtaining Restricted Biologics and Chemicals
If you wish to obtain biologics or chemicals found on the list below for your research, please contact the USU Institutional Biosafety Committee (IBC), who will coordinate with RIC to determine what requirements must be met to house the biologic or chemical on campus.
List of Restricted Materials
| AUSTRALIA GROUP/SCHEDULE 2 CHEMICALS UNDER CWC (30% OR MORE OF THE WEIGHT OF MIXTURE) | 1C350 - Chemicals that may be used as precursors for toxic chemical agents |
| Aresenic trichloride | 1C350(b)(1) |
| Benzilic acid | 1C350(b)(2) |
| Diethyl ethylphosphonate | 1C350(b)(3) |
| Diethyl methylphosphonate | 1C350(b)(4) |
| Diethyl methylphosphonite | 1C350(b)(5) |
| Diethyl-N,N-dimethylphosphoroamidate | 1C350(b)(6) |
| Diisopropylaminoethanethiol hydrochloride | 1C350(b)(7) |
| N,N-Diisopropyl-beta-aminoethane thiol | 1C350(b)(8) |
| N,N-Diisopropyl-beta-aminoethanol | 1C350(b)(9) |
| N,N-Diisopropyl-beta-aminoethyl chloride | 1C350(b)(10) |
| N,N-Diisopropyl-beta-aminoethyl chloride hydrochloride | 1C350(b)(11) |
| Dimethyl ethylphosphonate | 1C350(b)(12) |
| Dimethyl methylphosphonate | 1C350(b)(13) |
| N,N-dimethylamino-phosphoryl dichloride | 1C350(b)(14) |
| Ethyl phosphonous dichloride [Ethyl phosphinyl dichloride] | 1C350(b)(15) |
| Ethyl phosphonus difluoride [Ethyl phosphinyl difluoride] | 1C350(b)(16) |
| Ethyl phosphonyl dichloride | 1C350(b)(17) |
| Methylphosphonic acid | 1C350(b)(18) |
| Methylphosphonothioic dichloride | 1C350(b)(19) |
| Pinacolyl alcohol | 1C350(b)(20) |
| 3-Quinuclidinol | 1C350(b)(21) |
| Thiodiglycol | 1C350(b)(22) |
| AUSTRALIA GROUP/SCHEDULE 3 CHEMICALS UNDER CWC (30% OR MORE OF THE WEIGHT OF MIXTURE) | 1C350 - Chemicals that may be used as precursors for toxic chemical agents |
| Diethyl phosphite | 1C350(c)(1) |
| Dimethyl phosphite (dimethyl hydrogen phosphite) | 1C350(c)(2) |
| Ethyldiethanolamine | 1C350(c)(3) |
| Phosphorus oxychloride | 1C350(c)(4) |
| Phosphorus pentachloride | 1C350(c)(5) |
| Phosphorus trichloride | 1C350(c)(6) |
| Sulfur dichloride | 1C350(c)(7) |
| Sulfur monochloride | 1C350(c)(8) |
| Thionyl chloride | 1C350(c)(9) |
| Triethanolamine | 1C350(c)(10) |
| Triethyl phosphite | 1C350(c)(11) |
| Trimethyl phosphite | 1C350(c)(12) |
| OTHER AUSTRALIA GROUP NOT IDENTIFIED UNDER CWC (30% OR MORE OF THE WEIGHT OF MIXTURE) | 1C350 - Chemicals that may be used as precursors for toxic chemical agents |
| Ammonium hydrogen fluoride | 1C350(d)(1) |
| 2-Chloroethanol | 1C350(d)(2) |
| Diethylamine | 1C350(d)(3) |
| N,N-Diethylaminoethanol | 1C350(d)(4) |
| Diethyl chlorophosphite | 1C350(d)(5) |
| O,O-Diethyl phosphorodithioate | 1C350(d)(6) |
| O,O-Diethyl phosphorothioate | 1C350(d)(7) |
| Di-isopropylamine | 1C350(d)(8) |
| Dimethylamine | 1C350(d)(9) |
| Dimethylamine hydrochloride | 1C350(d)(10) |
| Ethyl chlorofluorophosphate | 1C350(d)(11) |
| Ethyl dichlorophosphate | 1C350(d)(12) |
| Ethyl difluorophosphate | 1C350(d)(13) |
| Hydrogen fluoride | 1C350(d)(14) |
| 3-Hydroxyl-1-methylpiperidine | 1C350(d)(15) |
| Methyl benzilate | 1C350(d)(16) |
| Methyl chlorofluorophosphate | 1C350(d)(17) |
| Methyl dichlorophosphate | 1C350(d)(18) |
| Methyl difluorophosphate | 1C350(d)(19) |
| N,N Diethylacetamidine | 1C350(d)(20) |
| N,N-Diethylbutanamidine | 1C350(d)(21) |
| N,N-Diethylformamidine | 1C350(d)(22) |
| N,N Diethylisobutanamidine | 1C350(d)(23) |
| N,N-Diethylpropanamidine | 1C350(d)(24) |
| N,N-Diisopropylbutanamidine | 1C350(d)(25) |
| N,N-Diisopropylformamidine | 1C350(d)(26) |
| N,N-Dimethylacetamidine | 1C350(d)(27) |
| N,N-Dimethylbutanamidine | 1C350(d)(28) |
| N,N-Dimethylformamidine | 1C350(d)(29) |
| N,N-Dimethylisobutanamidine | 1C350(d)(30) |
| N,N-Dimethylpropanamidine | 1C350(d)(31) |
| N,N-Dipropylacetamidine | 1C350(d)(32) |
| N,N-Dipropylbutanamidine | 1C350(d)(33) |
| N,N-Dipropylformamidine | 1C350(d)(34) |
| N,N-Dipropylisobutanamidine | 1C350(d)(35) |
| N,N-Dipropylpropanamidine | 1C350(d)(36) |
| Phosphorus pentasulfide | 1C350(d)(37) |
| Pinacolone | 1C350(d)(38) |
| Potassium bifluoride | 1C350(d)(39) |
| Potassium cyanide | 1C350(d)(40) |
| Potassium fluoride | 1C350(d)(41) |
| 3-Quinuclidone | 1C350(d)(42) |
| Sodium bifluoride | 1C350(d)(43) |
| Sodium cyanide | 1C350(d)(44) |
| Sodium fluoride | 1C350(d)(45) |
| Sodium hexafluorosilicate | 1C350(d)(46) |
| Sodium sulfide | 1C350(d)(47) |
| Triethanolamine hydrochloride | 1C350(d)(48) |
| Tri-isopropyl phosphite | 1C350(d)(49) |
| AMMONIUM NITRATE, INCLUDING FERTILIZERS, AND FERTILIZER BLENDS CONTAINING 15% A.N. (EXCEPT LIQUID) | 1C997 |
| CWC SCHEDULE 2 AND 3 CHEMICALS NOT IDENTIFIED IN ECCN 1C350 OR SUBJECT TO ITAR | 1C355 |
| PFIB: 1,1,3,3,3-Pentafluoro-2-(trifluoromethyl)-1-propene (C.A.S. 382-21-8) and mixtures in which PFIB constitutes more than 1 percent of the weight of the mixture | 1C355(a)(1)(a) |
| Chemicals, except for those listed in Schedule 1, containing a phosphorus atom to which is bonded one methyl, ethyl, or propyl (normal or iso) group but not further carbon atoms. | 1C355(a)(2)(a) |
| FAMILY: N,N-Dialkyl (Me, Et, n-Pr or i-Pr) phosphoramidic dihalides | 1C355(a)(2)(b) |
| FAMILY: Dialkyl (Me, Et, n-Pr or i-Pr) N,N-dialkyl (Me, Et, n-Pr, or i-Pr)-phosphoramidates; | 1C355(a)(2)(c) |
| FAMILY: N,N-Dialkyl (Me, Et, n-Pr or i-Pr) aminoethyl-2-chlorides and corresponding protonated salts | 1C355(a)(2)(d) |
| FAMILY: N,N-Dialkyl (Me, Et, n-Pr or i-Pr) aminoethane-2-ols and corresponding protonated salts | 1C355(a)(2)(e) |
| FAMILY: N,N-Dialkyl (Me, Et, n-Pr or i-Pr) aminoethane-2-thiols and corresponding protonated salts | 1C355(a)(2)(f) |
| Phosgene: Carbonyl dichloride (C.A.S. 75-44-5) | 1C355(b)(1)(a) |
| Cyanogen chloride | 1C355(b)(1)(b) |
| Hydrogen cyanide | 1C355(b)(1)(c) |
| Chloropicrin: Trichloronitromethane | 1C355(b)(1)(d) |
| Methyldiethanolamine | 1C355(b)(2)(b) |
| VIRUSES IDENTIFIED BY THE AUSTRALIA GROUP | 1C351(a) |
| African horse sickness virus | 1C351(a)(1) |
| African swine fever virus | 1C351(a)(2) |
| Andes virus | 1C351(a)(3) |
| Avian influenza (AI) viruses identified as having high pathogenicity (HP), as follows: | 1C351(a)(4) |
| a.4.a. AI viruses that have an intravenous pathogenicity index (IVPI) in 6-week-old chickens greater than 1.2; or | |
| a.4.b. AI viruses that cause at least 75% mortality in 4- to 8-week-old chickens infected intravenously | |
| Bluetongue virus | 1C351(a)(5) |
| Chapare virus | 1C351(a)(6) |
| Chikungunya virus | 1C351(a)(7) |
| Choclo virus | 1C351(a)(8) |
| Classical swine fever virus (Hog cholera virus) | 1C351(a)(9) |
| Crimean-Congo hemorrhagic fever virus | 1C351(a)(10) |
| Dobrava-Belgrade virus | 1C351(a)(11) |
| Eastern equine encephalitis virus | 1C351(a)(12) |
| Ebolavirus (includes all members of the Ebolavirus genus) | 1C351(a)(13) |
| Foot-and-mouth disease virus | 1C351(a)(14) |
| Goatpox virus | 1C351(a)(15) |
| Guanarito virus | 1C351(a)(16) |
| Hantaan virus | 1C351(a)(17) |
| Hendra virus (Equine morbillivirus) | 1C351(a)(18) |
| Japanese encephalitis virus | 1C351(a)(19) |
| Junin virus | 1C351(a)(20) |
| Kyasanur Forest disease virus | 1C351(a)(21) |
| Laguna Negra virus | 1C351(a)(22) |
| Lassa virus | 1C351(a)(23) |
| Louping ill virus | 1C351(a)(24) |
| Lujo virus | 1C351(a)(25) |
| Lumpy skin disease virus | 1C351(a)(26) |
| Lymphocytic choriomeningitis virus | 1C351(a)(27) |
| Machupo virus | 1C351(a)(28) |
| Marburgvirus (includes all members of the Marburgvirus genus) | 1C351(a)(29) |
| Middle East respiratory syndrome-related coronavirus (MERS-related coronavirus) | 1C351(a)(30) |
| Monkeypox virus | 1C351(a)(31) |
| Murray Valley encephalitis virus | 1C351(a)(32) |
| Newcastle disease virus | 1C351(a)(33) |
| Nipah virus | 1C351(a)(34) |
| Omsk hemorrhagic fever virus | 1C351(a)(35) |
| Oropouche virus | 1C351(a)(36) |
| Peste-des-petits ruminants virus | 1C351(a)(37) |
| Porcine Teschovirus | 1C351(a)(38) |
| Powassan virus | 1C351(a)(39) |
| Rabies virus and all other members of the Lyssavirus genus | 1C351(a)(40) |
| Reconstructed 1918 influenza virus | 1C351(a)(41) |
| Rift Valley fever virus; | 1C351(a)(42) |
| Rinderpest virus | 1C351(a)(43) |
| Rocio virus | 1C351(a)(44) |
| Sabia virus | 1C351(a)(45) |
| Seoul virus | 1C351(a)(46) |
| Severe acute respiratory syndrome-related coronavirus (SARS-related coronavirus) | 1C351(a)(47) |
| Sheeppox virus | 1C351(a)(48) |
| Sin Nombre virus | 1C351(a)(49) |
| St. Louis encephalitis virus | 1C351(a)(50) |
| Suid herpesvirus 1 (Pseudorabies virus; Aujeszky’s disease) | 1C351(a)(51) |
| Swine vesicular disease virus | 1C351(a)(52) |
| Tick-borne encephalitis virus (Far Eastern subtype, formerly known as Russian Spring-Summer encephalitis virus) | 1C351(a)(53) |
| Variola virus | 1C351(a)(54) |
| Venezuelan equine encephalitis virus | 1C351(a)(55) |
| Vesicular stomatitis virus | 1C351(a)(56) |
| Western equine encephalitis virus | 1C351(a)(57) |
| Yellow fever virus | 1C351(a)(58) |
| VIRUSES IDENTIFIED ON APHIS/CDC SELECT AGENTS LIST BUT NOT AUSTRALIA GROUP LIST | |
| Tick-borne encephalitis virus (Siberian subtype, formerly West Siberian virus - see 1C351.a.53 for Far Eastern subtype) | 1c351(b)(3) |
| BACTERIA IDENTIFIED BY THE AUSTRALIA GROUP | 1C351(c) |
| Bacillus anthracis | 1C351(c)(1) |
| Brucella abortus | 1C351(c)(2) |
| Brucella melitensis | 1C351(c)(3) |
| Brucella suis | 1C351(c)(4) |
| Burkholderia mallei (Pseudomonas mallei) | 1C351(c)(5) |
| Burkholderia pseudomallei (Pseudomonas pseudomallei) | 1C351(c)(6) |
| Chlamydia psittaci (Chlamydophila psittaci) | 1C351(c)(7) |
| Clostriduim argentinense (formerly known as Clostridium botulinum Type G), botulinum neurotoxin producing strains | 1C351(c)(8) |
| Clostridium baratii, botulinum neurotoxin producing strains | 1C351(c)(9) |
| Clostridium botulinum | 1C351(c)(10) |
| Clostridium butyricum, botulinum neurotoxin producing strains | 1C351(c)(11) |
| Clostridium perfringens, epsilon toxin producing types | 1C351(c)(12) |
| Coxiella burnetii | 1C351(c)(13) |
| Francisella tularensis | 1C351(c)(14) |
| Mycoplasma capricolum subspecies capripneumoniae (“strain F38”) | 1C351(c)(15) |
| Mycoplasma mycoides subspecies mycoides SC (small colony) (a.k.a. contagious bovine pleuropneumonia) | 1C351(c)(16) |
| Rickettsia prowazekii | 1C351(c)(17) |
| Salmonella enterica subspecies enterica serovar Typhi (Salmonella typhi) | 1C351(c)(18) |
| Shiga toxin producing Escherichia coli (STEC) of serogroups O26, O45, O103, O104, O111, O121, O145, O157, and other shiga toxin producing serogroups | 1C351(c)(19) |
| Shigella dysenteriae | 1C351(c)(20) |
| Vibrio cholerae | 1C351(c)(21) |
| Yersinia pestis | 1C351(c)(22) |
| TOXINS IDENTIFIED BY THE AUSTRALIA GROUP | 1C351(d) |
| Abrin | 1C351(d)(1) |
| Aflatoxins | 1C351(d)(2) |
| Botulinum toxins | 1C351(d)(3) |
| Brevetoxins | 1C351(d)(4) |
| Clostridium perfringens alpha, beta 1, beta 2, epsilon and iota toxins | 1C351(d)(5) |
| Conotoxins | 1C351(d)(6) |
| Diacetoxyscirpenol | 1C351(d)(7) |
| Gonyautoxins | 1C351(d)(8) |
| HT-2 toxin | 1C351(d)(9) |
| Microcystins (Cyanginosins) | 1C351(d)(10) |
| Modeccin | 1C351(d)(11) |
| Nodularins | 1C351(d)(12) |
| Palytoxin | 1C351(d)(13) |
| Ricin | 1C351(d)(14) |
| Saxitoxin | 1C351(d)(15) |
| Shiga toxins (shiga-like toxins, verotoxins, and verocytotoxins) | 1C351(d)(16) |
| Staphylococcus aureus enterotoxins, hemolysin alpha toxin, and toxic shock syndrome toxin (formerly known as Staphylococcus enterotoxin F) | 1C351(d)(17) |
| T-2 toxin | 1C351(d)(18) |
| Tetrodotoxin | 1C351(d)(19) |
| Viscumin (Viscum album lectin 1) | 1C351(d)(20) |
| Volkensin | 1C351(d)(21) |
| FUNGI AS FOLLOWS | 1C351(e) |
| Coccidioides immitis | 1C351(e)(1) |
| Coccidioides posadasii | 1C351(e)(2) |
| ITAR RESTRICTIONS | CCL (COMMERCE CONTROL LIST) DESIGNATION |
| Chemical Agents | Category XIV(a) |
| Biological Agents | Category XIV(b) |
| Chemical agent binary precurors and key precursors | Category XIV(c) |
| Defoliants | Category XIV(e) |